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The nucleic acid occurs as complex, high-molecular-weight biochemical macromolecule composed of nucleotide chains that convey genetic information. A usual nucleic acids come deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). Nucleic acids come witnessed altogether residing cells and viruses.
Nucleic acid, then known as because of its prevalence inside cellular nuclei, is the generic name of personal of biopolymers. A monomers are known as nucleotides, and to each one consists of threesome components: the nitrogen-bearing heterocyclic base (either a purine or a pyrimidine), a pentose sugar, and the phosphate group. Different nucleic acid types differ in the specific sugar noticed in their chain (e.g. DNA or even deoxyribonucleic acid contains Two-deoxyriboses). Likewise, a nitrogen-bearing bases imaginable in the deuce nucleic acids come different: adenine, cytosine, and guanine are possible around each RNA & DNA, when thymine is possible simply within DNA & uracil is possible just around RNA.
the sugars & phosphates around nucleic acids come attached to both more around an alternate chain across divided up o (forming a phosphodiester functional group). Using the conventional nomenclature, a carbons to which a phosphate groups come bonded come the Threesome' & a Five' carbons. the bases extend from either a glycosidic linkage to the Ace' carbon of the pentose ring.
Nucleic acids can be only-stranded or even double-stranded. The double-stranded nucleic acid consists of ii individual-stranded nucleic acids hydrogen-bonded together. RNA is commonly lone-stranded, however any given strand is in all likelihood to stack back upon itself to form double-helical regions. DNA is commonly double-stranded, though a few viruses have only-stranded DNA when their genome.
Nucleic acids come primarily biology's means of storing & transmitting genetic information, though RNA is also capable of acting as an enzyme.
Aquaphobic interaction of nucleic acids is ill understood.
Nucleic acids come insoluble withinside fermentation alcohol & insoluble in TCA.insoluble within cold a river, hot a river, dil HCl. Soluble inside dil NaOH, alcohol & HCl
There are various most common sources of DNA & RNA:
Calf thymus DNA will bring big linear DNA. It contains numerous breaks.
T4 phage DNA is circular & may be isolated intact.
Teichoic acids present in the cell walls of some gram-positive bacteria present a chemical structure resembling nucleic acids without a nucleobases.
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Molecular Recognition
Sequence-specific recognition of DNA using high affinity synthetic molecules, for the regulation of gene expression, by Professor Dervan's Group at the CIT, Pasadena, CA.
Anthracycline Intercalation
Details of anticancer anthracycline intercalated as DNA hexamer, illustrated from 3-D x-ray crystal images by Dr J.P. Miller at UMIST, Manchester, UK.
Mobile Group II Introns
Phylogenetic tree, secondary and ORF structure to identify and catalog group II introns in bacteria and other organisms, maintained by the Zimmerly Laboratory at the University of Calgary, Canada.
DNA Double Helix
Chime-dependent tutorial which permits image manipulation to help understand the 3-dimensional form of the structure, from John Tweedie and Massey University, New Zealand.
Left Handed DNA Hall of Fame
Devoted to correct and incorrect representations of left-handed DNA. Also has links related to left-handedness in nature, research, and in the news.
Crystallographic Studies
Information about the research carried out by Luca Jovine on crystallographic studies of RNA and DNA and protein structures, with contact details, request details for a copy of the PhD thesis and links to scientific publications.
NDB - The Nucleic Acid Database
Assembles and distributes structural information about nucleic acids. Includes databases, tutorials, and a musical atlas using different musical algorithms to provide a unique look into the structure of DNA.
TAB Molecular Probe Data Base
Information on about 4,300 synthetic oligonucleotides, mainly relevant to human diagnostics - from the Telematics Applications in Biotechnology Group at the National Institute for Cancer Research of Genoa, Italy.
BioServers
Contains user-friendly tools to launch DNA database searches, statistical analyses, and population modeling from a centralized workspace.
GeneProbes.org
Resource introducing DNA probe technologies, listing conferences, workshops and references with focus on marine biotoxins from Nelson, New Zealand.
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